Genetic variants in CYP and GST genes, smoking and risk for head and neck cancers: a gene–environment interaction hospital-based case–control study among Canadian Caucasians

Author:

ThekkePurakkal Akhil Soman1,Nicolau Belinda1,Burk Robert D2345,Franco Eduardo L67,Schlecht Nicolas F8

Affiliation:

1. Division of Oral Health and Society, Faculty of Dentistry, McGill University, Montreal, Canada

2. Department of Pediatrics (Genetics), Albert Einstein College of Medicine, Bronx, NY, USA

3. Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA

4. Department of Obstetrics and Gynecology and Women’s Health, Albert Einstein College of Medicine, Bronx, NY, USA

5. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA

6. Department of Oncology, McGill University, Montreal, Quebec, Canada

7. Department of Epidemiology, Biostatistics, and Occupational Health, Faculty of Medicine, McGill University, Montreal, Quebec, Canada

8. Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA

Funder

Canadian Institutes of Health Research

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference46 articles.

1. Chemistry and toxicology.;Hoffmann,1998

2. Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers;Bartsch;Cancer Epidemiol. Biomarkers Prev.,2000

3. GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: a mini-HuGE review;Geisler;Am. J. Epidemiol.,2001

4. Epidemiology of carcinogen metabolism genes and risk of squamous cell carcinoma of the head and neck;Ho;Head Neck,2007

5. Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review;Varela-Lema;Genet. Med.,2008

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