FGF2 and EGF induce epithelial–mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal

Author:

Schelch Karin12,Wagner Christina1,Hager Sonja1,Pirker Christine1,Siess Katharina1,Lang Elisabeth1,Lin Ruby23,Kirschner Michaela B2,Mohr Thomas1,Brcic Luka4,Marian Brigitte1,Holzmann Klaus1ORCID,Grasl-Kraupp Bettina1,Krupitza Georg5,Laszlo Viktoria67,Klikovits Thomas6,Dome Balazs689,Hegedus Balazs61011,Garay Tamas10,Reid Glen212,van Zandwijk Nico212,Klepetko Walter6,Berger Walter1,Grusch Michael1,Hoda Mir Alireza6

Affiliation:

1. Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria

2. Asbestos Diseases Research Institute (ADRI), Sydney, NSW, Australia

3. School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia

4. Institute of Pathology, Medical University of Graz, Graz, Austria

5. Department of Clinical Pathology, Medical University of Vienna, Vienna, Austria

6. Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna

7. Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

8. Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary

9. Department of Thoracic Surgery, National Institute of Oncology and Semmelweis University, Budapest, Hungary

10. MTA-SE Molecular Oncology Research Group, Hungarian Academy of Sciences, Budapest, Hungary

11. Department of Thoracic Surgery, Ruhrlandklinik, University Clinic Essen, University of Duisburg-Essen, Essen, Germany

12. School of Medicine, University of Sydney, NSW, Australia

Funder

Austrian National Bank (OeNB)

Innovative Interdisciplinary Cancer Research

Hans and Blanca Moser Foundation

Herzfelder Foundation

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference50 articles.

1. Pathogenesis of malignant pleural mesothelioma;Jaurand;Respirology,2005

2. The worldwide pandemic of asbestos-related diseases;Stayner;Annu. Rev. Public Health,2013

3. Malignant pleural mesothelioma: an epidemiological perspective;Robinson;Ann. Cardiothorac. Surg,2012

4. Malignant pleural mesothelioma;Tsao;J. Clin. Oncol,2009

5. Prognostic factors in patients with pleural mesothelioma: the European Organization for Research and Treatment of Cancer experience;Curran;J. Clin. Oncol,1998

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