Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung-Reference-Cited by-同舟云学术

Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung

Published:2018-05-17 Issue:8 Volume:39 Page:1079-1088
ISSN:0143-3334
Container-title:Carcinogenesis
language:en
Short-container-title:

Author:

Ashmore Joseph H¹,Luo Shaman¹²,Watson Christy J W¹,Lazarus Philip¹

Affiliation:

1. Department of Pharmaceutical Sciences, Washington State University, Spokane, WA, USA

2. Alkali Soil Natural Environmental Science Center, Northeast Forestry University, Harbin, Heilongjiang, China

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Link

http://academic.oup.com/carcin/article-pdf/39/8/1079/25333330/bgy065.pdf

Reference43 articles.

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4. Significance of reductases in the detoxification of the tobacco-specific carcinogen NNK;Maser;Trends Pharmacol. Sci,2004

5. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines;Hecht;Chem. Res. Toxicol,1998

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