Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences-Reference-Cited by-同舟云学术

Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences

Author:

Infante Lara Lorena¹,Fenner Sabine²,Ratcliffe Steven²,Isidro-Llobet Albert²,Hann Michael²,Bax Ben²³,Osheroff Neil¹⁴⁵^ORCID

Affiliation:

1. Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA

2. Platform Technology and Science, GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK

3. York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, UK

4. Department of Medicine (Hematology/Oncology), Vanderbilt University School of Medicine, Nashville, TN 37232, USA

5. VA Tennessee Valley Healthcare System, Nashville, TN 37212, USA

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

Reference69 articles.

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