1. Department of Internal Medicine, National Taiwan University Hospital , 7 Chung-Shan South Road, Taipei 100 , Taiwan
2. Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine , Taipei , Taiwan
3. National Institutes of Infectious Diseases and Vaccinology, National Health Research Institutes , Zhunan , Taiwan
4. Department of Internal Medicine, National Taiwan University Cancer Center , Taipei , Taiwan
5. School of medicine, National Taiwan University College of Medicine , Taipei , Taiwan