Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant-Reference-Cited by-同舟云学术

Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant

Published:2015-04-01 Issue:2 Volume:2 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Stripling Joshua¹,Kumar Ranjit²,Baddley John W.¹,Nellore Anoma¹,Dixon Paula¹,Howard Donna³,Ptacek Travis⁴,Lefkowitz Elliot J.²⁴,Tallaj Jose A.⁵,Benjamin William H.³,Morrow Casey D.⁶,Rodriguez J. Martin¹

Affiliation:

1. Division of Infectious Diseases, Department of Medicine

2. Center for Clinical and Translational Sciences

3. Departments of Pathology

4. Microbiology

5. Division of Cardiology, Department of Medicine

6. Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham

Abstract

We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.

Funder

School of Medicine, Comprehensive Cancer Center

Center for AIDS Research

Center for Clinical Translational Science

Heflin Center

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/2/2/ofv078/33621118/ofv078.pdf

Reference12 articles.