West Nile Virus Central Nervous System Infection in Patients Treated With Rituximab: Implications for Diagnosis and Prognosis, With a Review of Literature-Reference-Cited by-同舟云学术

West Nile Virus Central Nervous System Infection in Patients Treated With Rituximab: Implications for Diagnosis and Prognosis, With a Review of Literature

Published:2015 Issue:4 Volume:2 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Morjaria Sejal¹,Arguello Esther¹,Taur Ying¹,Sepkowitz Kent¹,Hatzoglou Vaios²,Nemade Ajay²,Rosenblum Marc³,Cavalcanti Marcela S.³,Palomba M. Lia⁴,Kaltsas Anna¹

Affiliation:

1. Infectious Disease Service, Department of Medicine

2. Neuroradiology Service, Department of Radiology

3. Departments of Pathology

4. Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York

Abstract

Abstract The spectrum of West Nile virus (WNV) infection continues to be elucidated. Many cases of WNV are asymptomatic; however, in immunocompromised patients, symptoms are more likely to be severe. We describe fatal WNV central nervous system disease in lymphoma patients who received rituximab, blunting the inflammatory response and complicating diagnosis.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/2/4/ofv136/33603239/ofv136.pdf

Reference11 articles.

1. Donor-derived West Nile virus infection in solid organ transplant recipients: report of four additional cases and review of clinical, diagnostic, and therapeutic features;Winston;Transplantation,2014

2. First isolation of West Nile virus from a patient with encephalitis in the United States;Huang;Emerg Infect Dis,2002

3. Impact of rituximab-associated B-cell defects on West Nile virus meningoencephalitis in solid organ transplant recipients;Levi;Clin Transplant,2010

4. Fatal West Nile virus infection after rituximab/fludarabine--induced remission for non-Hodgkin's lymphoma;Mawhorter;Clin Lymphoma Myeloma,2005

5. Rituximab-associated infections;Gea-Banacloche,2010

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