Primary Larynx Cryptococcus neoformans Infection: A Distinctive Clinical Entity

Author:

Bergeron Mathieu1,Gagné Andrée-Anne1,Côté Mathieu2,Chênevert Jacinthe3,Dubé Robert3,Pelletier René4

Affiliation:

1. Laval University

2. Otolaryngology

3. Anatomo-Pathology, Centre Hospitalier Universitaire de Québec

4. Medical Microbiology and Infectious Diseases, Centre Hospitalier Universitaire de Québec, L'Hôtel-Dieu de Québec, Quebec City, Canada

Abstract

Abstract Cryptococcus neoformans can directly infect the vocal cords. Endoscopic findings were undistinctive from most infiltrative diseases. Tissue biopsy was essential for the diagnosis. Inhaled corticosteroids can predispose to the infection, and fluconazole 400 mg daily for at least 6 weeks appeared to be minimal to achieve a permanent cure.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference20 articles.

1. Cryptococcosis;Chayakulkeeree;Infect Dis Clin North Am,2006

2. Human cryptococcosis: relationship of environmental and clinical strains of Cryptococcus neoformans var. neoformans from urban and rural areas;Delgado;Mycopathologia,2005

3. A case of vocal cord cyst with cryptococcal infection;Bamba;Otolaryngol Head Neck Surg,2005

4. Cryptococcosis of the larynx in a patient with AIDS: an unusual cause of fungal laryngitis;Browning;South Med J,1992

5. Cryptococcal infection of the vocal folds;Chang;Southeast Asian J Trop Med Public Health,2013

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