Viral Blips After Treatment Initiation During Acute Human Immunodeficiency Virus Infection-Reference-Cited by-同舟云学术

Viral Blips After Treatment Initiation During Acute Human Immunodeficiency Virus Infection

Published:2019-09-24 Issue:12 Volume:70 Page:2706-2709
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Crowell Trevor A¹²^ORCID,Pinyakorn Suteeraporn¹²,Sacdalan Carlo³,Kroon Eugène³,Colby Donn J³,Puttamaswin Suwanna³,Ubolyam Sasiwimol⁴,Trichavaroj Rapee⁵,Butterworth Oratai¹²,Turk Ellen¹²,Mccullough Corinne¹²,Chomont Nicolas⁶,de Souza Mark²³,Robb Merlin L¹²,Phanuphak Nittaya³,Ananworanich Jintanat¹²³⁷,

Affiliation:

1. US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

2. Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA

3. South East Asia Research Collaboration in HIV, Thai Red Cross AIDS Research Centre, Bangkok, Thailand

4. The HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Centre, Bangkok, Thailand

5. Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

6. Centre de Recherche du Centre Hospitalier de l’Université de Montréal and Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, Quebec, Canada

7. Department of Global Health, University of Amsterdam, Amsterdam, The Netherlands

Abstract

Abstract Transient viral blips ≥20 copies/mL were observed in 16.9% of acutely treated adults with HIV. Blip incidence increased from 0.0 (95% CI, 0.0–2.9)/100 person-years after ART in Fiebig I to 15.9 (7.6–29.2) in Fiebig V. Increasing viral load and Fiebig stage at ART initiation were independently predictive of blips.

Funder

Henry M. Jackson Foundation

US Department of the Army

Thai Government Pharmaceutical Organization

ViiV Healthcare

Gilead

Merck

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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