Drug non-adherence in hypertensive patients in Morocco, and its associated risk factors

Author:

Essayagh Touria1,Essayagh Meriem2,Essayagh Sanah3

Affiliation:

1. University Hassan First of Settat, Laboratoire Sciences et Technologies de la Santé, Institut Supérieur, des Sciences de la Santé, Settat, Morocco

2. University Mohammed V, Faculté de Médecine et de Pharmacie de Rabat, Morocco

3. University Hassan First of Settat, Laboratoire Agroalimentaire et Santé, Faculté des Sciences et Techniques, Settat, Morocco

Abstract

Abstract Aims Hypertension is a widespread public health problem; unfortunately, non-adherence to the treatment hinders the control of high blood pressure. Drug non-adherence is the degree to which a patient does not follow the prescription. We aimed to assess the extent of drug non-adherence among hypertensive patients treated in Meknes and identify risk factors associated with inobservance. Methods and results Between November and December 2017, we conducted a cross-sectional study enrolling 922 hypertensive patients managed at Meknes’s primary healthcare facilities (PHCF) using the multistage sampling method. We interviewed patients face to face to collect their socio-demographic characteristics, lifestyle behaviours, clinical parameters, and the relationship between the care system, the patient, and the physician. A multivariate logistic regression analysis highlighted the risk factors associated with drug non-adherence. The prevalence of drug non-adherence was 91% with a mean age of 61 ± 11 years (mean ± standard deviation) and a male/female ratio of 1/3. Risk factors associated with drug non-adherence were: (i) male sex [adjusted odds ratio (AOR) = 2.5, 95% confidence interval (CI) (1.26–5.10)]; (ii) monthly income per household <150$ [AOR = 4.47, 95% CI (1.22–16.34)]; (iii) monthly income per household 150–200$ [AOR = 4.44, 95% CI (1.04–18.93)]; (iv) bad relationship with the healthcare system [AOR = 2.17, 95% CI (1.29–3.67)]; and (v) uncontrolled blood pressure [AOR = 1.87, 95% CI (1.15–3.02)]. Conclusion The prevalence of drug non-adherence is general among hypertensive patients in Meknes. Prevention should: (i) ensure the availability of adequate stocks of the anti-hypertensive drug at the PHCF; (ii) secure sufficient drug stocks to treat the poorest patients first; and (iii) improve blood pressure control in patients.

Publisher

Oxford University Press (OUP)

Subject

Advanced and Specialised Nursing,Medical–Surgical,Cardiology and Cardiovascular Medicine

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