Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase-Reference-Cited by-同舟云学术

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Published:2003-11-25 Issue:2 Volume:13 Page:159-170
ISSN:1460-2083
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Jankowsky Joanna L.,Fadale Daniel J.,Anderson Jeffrey,Xu Guilian M.,Gonzales Victoria,Jenkins Nancy A.,Copeland Neal G.,Lee Michael K.,Younkin Linda H.,Wagner Steven L.,Younkin Steven G.,Borchelt David R.

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/13/2/159/17240925/ddh019.pdf

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3. Masters, C.L., Simms, G., Weinman, N.A., Multhaup, G., McDonald, B.L. and Beyreuther, K. (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl Acad. Sci. USA, 82, 4245–4249.

4. Roher, A., Wolfe, D., Palutke, M. and KuKurga, D. (1986) Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein. Proc. Natl Acad. Sci. USA, 83, 2662–2666.

5. Shoji, M., Golde, T.E., Ghiso, J., Cheung, T.T., Estus, S., Shaffer, L.M., Cai, X.-D., McKay, D.M., Tintner, R., Frangione, B. and Younkin, S.G. (1992) Production of the Alzheimer amyloid β protein by normal proteolytic processing. Science, 258, 126–129.

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