Automated selection of changepoints using empirical P-values and trimming

Author:

Quinn Matthew1,Chung Arlene2,Glass Kimberly134ORCID

Affiliation:

1. Department of Biostatistics, Harvard T.H. Chan School of Public Health , Boston, Massachusetts, USA

2. Department of Biostatistics & Bioinformatics, Duke School of Medicine , Durham, North Carolina, USA

3. Channing Division of Network Medicine, Brigham and Women’s Hospital , Boston, Massachusetts, USA

4. Department of Medicine, Harvard Medical School , Boston, Massachusetts, USA

Abstract

Abstract Objectives One challenge that arises when analyzing mobile health (mHealth) data is that updates to the proprietary algorithms that process these data can change apparent patterns. Since the timings of these updates are not publicized, an analytic approach is necessary to determine whether changes in mHealth data are due to lifestyle behaviors or algorithmic updates. Existing methods for identifying changepoints do not consider multiple types of changepoints, may require prespecifying the number of changepoints, and often involve nonintuitive parameters. We propose a novel approach, Automated Selection of Changepoints using Empirical P-values and Trimming (ASCEPT), to select an optimal set of changepoints in mHealth data. Materials and Methods ASCEPT involves 2 stages: (1) identification of a statistically significant set of changepoints from sequential iterations of a changepoint detection algorithm; and (2) trimming changepoints within linear and seasonal trends. ASCEPT is available at https://github.com/matthewquinn1/changepointSelect. Results We demonstrate ASCEPT’s utility using real-world mHealth data collected through the Precision VISSTA study. We also demonstrate that ASCEPT outperforms a comparable method, circular binary segmentation, and illustrate the impact when adjusting for changepoints in downstream analysis. Discussion ASCEPT offers a practical approach for identifying changepoints in mHealth data that result from algorithmic updates. ASCEPT’s only required parameters are a significance level and goodness-of-fit threshold, offering a more intuitive option compared to other approaches. Conclusion ASCEPT provides an intuitive and useful way to identify which changepoints in mHealth data are likely the result of updates to the underlying algorithms that process the data.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Health Informatics

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