Northern lights assay: a versatile method for comprehensive detection of DNA damage

Author:

Gudmundsson Bjarki123,Thormar Hans G13,Sigurdsson Albert1,Dankers Wendy1,Steinarsdottir Margret2,Hermanowicz Stefan14,Sigurdsson Stefan14,Olafsson David15,Halldorsdottir Anna M5,Meyn Stephen678,Jonsson Jon J12ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Iceland, Reykjavik IS-101, Iceland

2. Department of Genetics and Molecular Medicine, Landspitali–National University Hospital, Reykjavik IS-101, Iceland

3. Lifeind ehf., Reykjavik IS-101, Iceland

4. Faculty of Medicine, University of Iceland, Reykjavik IS-101, Iceland

5. The Blood Bank, Landspitali–National University Hospital, Reykjavik IS-101, Iceland

6. Department of Paediatrics, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada

7. University of Toronto, Toronto, ON, M5S 1A8, Canada

8. Center for Human Genomics and Precision Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53705, USA

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference46 articles.

1. A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents;Sasaki;Cancer Res.,1973

2. Defective repair replication of DNA in xeroderma pigmentosum;Cleaver;Nature,1968

3. Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks;Ismail;J. Biol. Chem.,2005

4. Mutagenicity, cytotoxicity and DNA crosslinking in V79 Chinese hamster cells treated with cis- and trans-Pt(II) diamminedichloride;Zwelling;Mutat. Res.,1979

5. DNA cross-linking and cytotoxicity induced by cis-diamminedichloroplatinum(II) in human normal and tumor cell lines;Laurent;Cancer Res.,1981

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