Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy-Reference-Cited by-同舟云学术

Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy

Published:2018-07-16 Issue:16 Volume:46 Page:8326-8346
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Kannan Annapoorna¹²,Bhatia Kanchan¹²,Branzei Dana³⁴,Gangwani Laxman¹²⁵

Affiliation:

1. Center of Emphasis in Neurosciences, Department of Biomedical Sciences, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905

2. Department of Biomedical Sciences, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905

3. The FIRC Institute of Molecular Oncology Foundation, IFOM Foundation, Via Adamello 16, Milan 20139, Italy

4. Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (IGM-CNR), Via Abbiategrasso 207, Pavia 27100, Italy

5. Graduate School of Biomedical Sciences, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905, USA

Funder

National Institutes of Health

Muscular Dystrophy Association

Italian Association for Cancer Research

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/46/16/8326/25802757/gky641.pdf

Reference78 articles.

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3. Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick;Burghes;Nat. Rev. Neurosci.,2009

4. Spinal muscular atrophy: a deficiency in a ubiquitous protein; a motor neuron-specific disease;Monani;Neuron,2005

5. Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity;Bowerman;J. Mol. Neurosci.,2007

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