Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature

Author:

O’Sullivan Mary E1ORCID,Poitevin Frédéric23,Sierra Raymond G4,Gati Cornelius25,Dao E Han3,Rao Yashas4,Aksit Fulya4,Ciftci Halilibrahim4,Corsepius Nicholas2,Greenhouse Robert1,Hayes Brandon4,Hunter Mark S4,Liang Mengling4,McGurk Alex4,Mbgam Paul4,Obrinsky Trevor4,Pardo-Avila Fátima2,Seaberg Matthew H4,Cheng Alan G1,Ricci Anthony J1,DeMirci Hasan235ORCID

Affiliation:

1. Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Palo Alto, CA, USA, 94305

2. Department of Structural Biology, Stanford University, Palo Alto, CA, USA, 94305

3. Stanford PULSE Institute, SLAC National Laboratory, Menlo Park, CA, USA, 94025

4. Linac Coherent Light Source, SLAC National Laboratory, Menlo Park, CA, USA, 94025

5. Biosciences Division, SLAC National Laboratory, Menlo Park, CA, USA, 94025

Funder

National Institutes of Health

NSF Science and Technology

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference54 articles.

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2. Bacterial Protein Synthesis as a Target for Antibiotic Inhibition;Arenz;Cold Spring Harb. Perspect. Med.,2016

3. Cochlear signs of streptomycin intoxication;Hawkins;J. Pharmacol. Exp. Ther.,1950

4. Streptomycin-induced oversuppression in E. Coli;Gorini;Proc. Natl. Acad. Sci. U.S.A.,1964

5. Streptomycin, suppression, and the code;Davies;Proc. Natl. Acad. Sci. U.S.A.,1964

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