Viewpoint: Antimicrobial Resistance Diagnostics Use Accelerator: Qualitative Research on Adherence to Prescriptions

Author:

Compaoré Adélaïde1,Ekusai-Sebatta Deborah2,Kaawa-Mafigiri David3,Kukula Vida4,Odopey Selase4,Kapisi James2,Hopkins Heidi5,Kiemde François1,Tinto Halidou1,Baiden Rita4,Olliaro Piero67,Nkeramahame Juvenal6,Dittrich Sabine689,Horgan Philip61011,Awor Phyllis,Ekusai-Sebatta Deborah,Hopkins Heidi,Kaawa-Mafigiri David,Kapisi James,Kitutu Freddy Eric,Rutebemberwa Elizeus,Sserwanga Asadu,Adjei Alexander,Baiden Rita,Kukula Vida,Compaoré Adélaïde,Kiemde François,Tinto Halidou,Valia Daniel,

Affiliation:

1. Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santé , Nanoro , Burkina Faso

2. Infectious Diseases Research Collaboration

3. Department of Social Work and Social Administration, School of Social Sciences, Makerere University , Kampala , Uganda

4. Social Science Department, Dodowa Health Research Centre , Ghana

5. Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine , United Kingdom

6. Department of Medical Affairs, FIND , Geneva , Switzerland

7. International Severe Acute Respiratory and Emerging Infection Consortium, Pandemic Sciences Institute, and

8. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford , United Kingdom

9. Deggendorf Institute of Technology, European Campus Rottal Inn , Pfarrkirchen , Germany

10. Nuffield Department of Medicine, Big Data Institute, University of Oxford

11. Department of Medicine, Evidence & Impact - Oxford , United Kingdom

Abstract

Abstract In this Viewpoint, the authors explore the determinants of patients’ prescription adherence behaviors as part of FIND's Advancing Access to Diagnostic Innovation essential for Universal Health Coverage and AMR Prevention (ADIP) trials (ClinicalTrials.gov identifier: NCT04081051). Research findings from Burkina Faso, Ghana, and Uganda show that basic knowledge and understanding of prescription instructions are essential for adherence and can be improved through better communication. However, there are a range of other factors that influence adherence, some of which can be influenced through tailored communication messages from healthcare workers. These messages may contribute to changes in adherence behavior but may require other reinforcing interventions to be effective. Finally, there are some drivers of nonadherence centered around costs and time pressure that require other forms of intervention.

Funder

Swiss Agency for Development and Cooperation

Federal Ministry of Economic Cooperation and Development

UK Department For International Development

Foreign, Commonwealth and Development Office

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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