A Genomic Perspective on the Near-term Impact of Doxycycline Post-exposure Prophylaxis on <i>Neisseria gonorrhoeae</i> Antimicrobial Resistance-Reference-Cited by-同舟云学术

A Genomic Perspective on the Near-term Impact of Doxycycline Post-exposure Prophylaxis on Neisseria gonorrhoeae Antimicrobial Resistance

Published:2023-05-04 Issue:5 Volume:77 Page:788-791
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Mortimer Tatum D¹^ORCID,Grad Yonatan H¹^ORCID

Affiliation:

1. Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health , Boston, Massachusetts , USA

Abstract

Abstract Pre-existing tetracycline resistance in Neisseria gonorrhoeae limits the effectiveness of post-exposure prophylaxis (PEP) with doxycycline against gonorrhea, and selection for tetracycline resistance may influence prevalence of multi-drug resistant strains. Using genomic and antimicrobial susceptibility data from N. gonorrhoeae, we assessed the near-term impact of doxycycline PEP on N. gonorrhoeae resistance.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciad279/50317317/ciad279.pdf

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