Significant Association of Cutavirus With Parapsoriasis en Plaques: High Prevalence Both in Skin Swab and Biopsy Samples-Reference-Cited by-同舟云学术

Significant Association of Cutavirus With Parapsoriasis en Plaques: High Prevalence Both in Skin Swab and Biopsy Samples

Published:2023-05-26 Issue:7 Volume:77 Page:987-990
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Mohanraj Ushanandini¹^ORCID,Konttinen Tuomas¹²³^ORCID,Salava Alexander⁴^ORCID,Väkevä Liisa⁴^ORCID,Ranki Annamari⁴^ORCID,Söderlund-Venermo Maria¹^ORCID

Affiliation:

1. Department of Virology, University of Helsinki , Helsinki , Finland

2. Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital , Helsinki , Finland

3. Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki , Helsinki , Finland

4. Department of Dermatology, Allergology, and Venereology, University of Helsinki and Helsinki University Central Hospital , Helsinki , Finland

Abstract

Abstract Cutavirus (CuV) is associated with cutaneous T-cell lymphoma (CTCL), of which parapsoriasis is a precursor. Our study reveals a significantly higher CuV-DNA prevalence in skin swabs of parapsoriasis patients (6/13; 46.2%) versus those of healthy adults (1/51; 1.96%). Eight patients (8/12; 66.7%) had CuV DNA in biopsied skin, and 4 developed CTCL.

Funder

Finnish-Norwegian Medical Foundation

Ida Montin Foundation

Viral Disease Research Foundation

Sigrid Jusélius Foundation

Life and Health Medical Support Association

Swedish Cultural Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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