Lessons From COVID-19 for Pandemic Preparedness: Proceedings From a Multistakeholder Think Tank

Author:

Narayanasamy Shanti12ORCID,Curtis Lesley H34,Hernandez Adrian F35,Woods Christopher W12,Moody M Anthony67,Sulkowski Mark8,Turbett Sarah E91011,Baden Lindsey R12,Gulick Roy M13,Pau Alice K14,Adam Stacey J15,Marks Peter16,Stockbridge Norman L16,Dobbins John R17,Krofah Esther18,Leav Brett19,Pang Phil20,Roessig Lothar21,Vedin Ola22,Waldstreicher Joanne23,Berman Stacey Cromer24,Cremisi Henry24,Schofield Lesley25,Gandhi Rajesh T911,Naggie Susanna13

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, Duke University , Durham, North Carolina , USA

2. Hubert-Yeargan Center for Global Health, Duke University , Durham, North Carolina , USA

3. Duke Clinical Research Institute , Durham, North Carolina , USA

4. Department of Population Health Sciences, Duke University School of Medicine , Durham, North Carolina , USA

5. Division of Cardiology, Department of Medicine, Duke University , Durham, North Carolina , USA

6. Department of Pediatrics, Duke University School of Medicine , Durham, North Carolina , USA

7. Duke Human Vaccine Institute , Durham, North Carolina , USA

8. Johns Hopkins University School of Medicine , Baltimore, Maryland , USA

9. Division of Infectious Diseases, Massachusetts General Hospital , Boston, Massachusetts , USA

10. Department of Pathology, Massachusetts General Hospital , Boston, Massachusetts , USA

11. Department of Medicine, Harvard Medical School , Boston, Massachusetts , USA

12. Brigham and Women's Hospital , Boston, Massachusetts , USA

13. Weill Cornell Medicine , New York, New York , USA

14. National Institutes of Health , Bethesda, Maryland , USA

15. Foundation for the National Institutes of Health , North Bethesda, Maryland , USA

16. US Food and Drug Administration , Silver Spring, Maryland , USA

17. Eli Lilly and Company , Indianapolis, Indiana , USA

18. FasterCures & Center for Public Health, Milken Institute , Washington, DC , USA

19. Moderna , Cambridge, Massachusetts , USA

20. Vir Biotechnology, Inc , San Francisco, California , USA

21. Bayer , Wuppertal , Germany

22. Boehringer Ingelheim AB , Stockholm , Sweden

23. Johnson & Johnson , New Brunswick, New Jersey , USA

24. AstraZeneca , Wilmington, Delaware , USA

25. Novartis Pharmaceuticals Corporation , East Hanover, New Jersey , USA

Abstract

Abstract While the coronavirus disease 2019 (COVID-19) pandemic continues to present global challenges, sufficient time has passed to reflect on lessons learned and use those insights to inform policy and approaches to prepare for the next pandemic. In May 2022, the Duke Clinical Research Institute convened a think tank with thought leaders from academia, clinical practice, the pharmaceutical industry, patient advocacy, the National Institutes of Health, the US Food and Drug Administration, and the Centers for Disease Control and Prevention to share, firsthand, expert knowledge of the insights gained from the COVID-19 pandemic and how this acquired knowledge can help inform the next pandemic response. The think tank focused on pandemic preparedness, therapeutics, vaccines, and challenges related to clinical trial design and scale-up during the early phase of a pandemic. Based on the multi-faceted discussions, we outline 10 key steps to an improved and equitable pandemic response.

Funder

Duke Clinical Research Institute

DCRI

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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