Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antiviral Prescribing Gaps Among Nonhospitalized High-Risk Adults

Author:

Levy Matthew E1ORCID,Burrows Evanette1,Chilunda Vanessa1,Pawloski Pamala A2,Heaton Phillip R3,Grzymski Joseph45,Goldman Jason D678,McEwen Lisa M1,Wyman Dana1,Dei Rossi Andrew1,Dai Hang1,Isaksson Magnus1,Washington Nicole L1,Basler Tracy1,Tsan Kevin1,Nguyen Jason1,Ramirez Jimmy1,Sandoval Efren1,Lee William1,Lu James1,Luo Shishi1

Affiliation:

1. Helix , San Mateo, California , USA

2. HealthPartners Institute , Minneapolis, Minnesota , USA

3. Department of Pathology and Laboratory Medicine, HealthPartners , Bloomington, Minnesota , USA

4. Department of Internal Medicine, University of Nevada Reno, School of Medicine , Reno, Nevada , USA

5. Renown Health , Reno, Nevada , USA

6. Providence St. Joseph Health System , Renton, Washington , USA

7. Swedish Center for Research and Innovation, Swedish Medical Center , Seattle, Washington , USA

8. Division of Infectious Disease, University of Washington , Seattle, Washington , USA

Abstract

Abstract Within a multistate clinical cohort, SARS-CoV-2 antiviral prescribing patterns were evaluated from April 2022–June 2023 among nonhospitalized patients with SARS-CoV-2 with risk factors for severe COVID-19. Among 3247 adults, only 31.9% were prescribed an antiviral agent (87.6% nirmatrelvir/ritonavir, 11.9% molnupiravir, 0.5% remdesivir), highlighting the need to identify and address treatment barriers.

Funder

Helix

Desert Research Institute

University of Nevada

Reno School of Medicine

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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