First Known Human Death After Infection With the Avian Influenza A/H3N8 Virus: Guangdong Province, China, March 2023-Reference-Cited by-同舟云学术

First Known Human Death After Infection With the Avian Influenza A/H3N8 Virus: Guangdong Province, China, March 2023

Published:2023-08-09 Issue: Volume: Page:
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Zhuang Yali¹,Wang Man²,Liang Lijun³,Mao Yunxia⁴,Wang Kaibin⁵⁶,Yang Shuhuan⁷,Deng Aiping¹,Zeng Kewen⁸,Zhang Yingtao¹,Zhang Guanting¹,Kang Min¹,Li Baisheng³,Zhang Meng¹,Ye Shinan²

Affiliation:

1. Institute of Infectious Disease Control and Prevention, Guangdong Provincial Center for Disease Control and Prevention , Guangzhou, Guangdong , P.R. China

2. General Office, Zhongshan Center for Disease Control and Prevention , Zhongshan, Guangdong , P.R. China

3. Institute of Pathogenic Microbiology, Guangdong Provincial Center for Disease Control and Prevention , Guangzhou, Guangdong , P.R. China

4. Institute of Infectious Disease Control and Prevention, Zhongshan Center for Disease Control and Prevention , Zhongshan, Guangdong , P.R. China

5. Guangdong Provincial Field Epidemiology Training Program, Guangdong Provincial Center for Disease Control and Prevention , Guangzhou, Guangdong , P.R. China

6. Department of Disinfection and Vector Control, Guangzhou Tianhe District Center for Disease Control and Prevention , Guangzhou, Guangdong , P.R. China

7. Institute of Pathogenic Microbiology, Zhongshan Center for Disease Control and Prevention , Zhongshan, Guangdong , P.R. China

8. Department of Prevention & Healthcare, Zhongshan City People's Hospital , Zhongshan, Guangdong , P.R. China

Abstract

Abstract Here, we report on a case of human infection with the H3N8 avian influenza virus. The patient had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without mammalian-adaptive mutations. This suggests that avian influenza (A/H3N8) virus infection could be lethal for immunocompromised persons.

Funder

Guangdong Medical Research Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciad462/51278825/ciad462.pdf

Reference18 articles.

1. Human co-infection with novel avian influenza A H7N9 and influenza A H3N2 viruses in Jiangsu Province, China;Zhu;Lancet (London, England),2013

2. Influenza virus reservoirs and intermediate hosts: dogs, horses, and new possibilities for influenza virus exposure of humans;Parrish;J Virol,2015

3. Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses;Liu;Lancet (London, England),2013