Long-Term Safety and Efficacy of Subcutaneous Methylnaltrexone in Patients with Opioid-Induced Constipation and Chronic Noncancer Pain: A Phase 3, Open-Label Trial-Reference-Cited by-同舟云学术

Long-Term Safety and Efficacy of Subcutaneous Methylnaltrexone in Patients with Opioid-Induced Constipation and Chronic Noncancer Pain: A Phase 3, Open-Label Trial

Published:2017-07-27 Issue:8 Volume:18 Page:1496-1504
ISSN:1526-2375
Container-title:Pain Medicine
language:en
Short-container-title:

Author:

Webster Lynn R.¹,Michna Edward²,Khan Arif³⁴,Israel Robert J.⁵,Harper Joseph R.⁵

Affiliation:

1. Vice President Scientific Affairs, PRA Health Sciences, Salt Lake City, Utah

2. Director, Pain Trials Center, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts

3. Medical Director, Principal Investigator, Northwest Clinical Research Center, Bellevue, Washington

4. Adjunct Professor of Psychiatry, Duke University Medical Center, Durham, North Carolina

5. Salix Pharmaceuticals, Raleigh, North Carolina, USA

Publisher

Oxford University Press (OUP)

Subject

Anesthesiology and Pain Medicine,Neurology (clinical),General Medicine

Link

http://academic.oup.com/painmedicine/article-pdf/18/8/1496/24350574/pnx148.pdf

Reference28 articles.

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3. Systematic literature review and meta-analysis of the efficacy and safety of prescription opioids, including abuse-deterrent formulations, in non-cancer pain management;Michna;Pain Med,2014

4. Emerging treatments in neurogastroenterology: A multidisciplinary working group consensus statement on opioid-induced constipation;Camilleri;Neurogastroenterol Motil,2014

5. Managing opioid-induced constipation in advanced illness: Focus on methylnaltrexone bromide;Clemens;Ther Clin Risk Manag,2010

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