Lifetime risk of maternal near miss morbidity: a novel indicator of maternal health

Author:

Gazeley Ursula12ORCID,Polizzi Antonino3ORCID,Romero-Prieto Julio E2ORCID,Aburto José Manuel234ORCID,Reniers Georges2ORCID,Filippi Veronique1ORCID

Affiliation:

1. Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine , London, UK

2. Department of Population Health, London School of Hygiene and Tropical Medicine , London, UK

3. Leverhulme Centre for Demographic Science, Nuffield College and Department of Sociology, University of Oxford , Oxford, UK

4. Interdisciplinary Centre on Population Dynamics, University of Southern Denmark , Odense, Denmark

Abstract

Abstract Background The lifetime risk of maternal death quantifies the probability that a 15-year-old girl will die of a maternal cause in her reproductive lifetime. Its intuitive appeal means it is a widely used summary measure for advocacy and international comparisons of maternal health. However, relative to mortality, women are at an even higher risk of experiencing life-threatening maternal morbidity called ‘maternal near miss’ (MNM) events—complications so severe that women almost die. As maternal mortality continues to decline, health indicators that include information on both fatal and non-fatal maternal outcomes are required. Methods We propose a novel measure—the lifetime risk of MNM—to estimate the cumulative risk that a 15-year-old girl will experience a MNM in her reproductive lifetime, accounting for mortality between the ages 15 and 49 years. We apply the method to the case of Namibia (2019) using estimates of fertility and survival from the United Nations World Population Prospects along with nationally representative data on the MNM ratio. Results We estimate a lifetime risk of MNM in Namibia in 2019 of between 1 in 40 and 1 in 35 when age-disaggregated MNM data are used, and 1 in 38 when a summary estimate for ages 15–49 years is used. This compares to a lifetime risk of maternal death of 1 in 142 and yields a lifetime risk of severe maternal outcome (MNM or death) of 1 in 30. Conclusions The lifetime risk of MNM is an urgently needed indicator of maternal morbidity because existing measures (the MNM ratio or rate) do not capture the cumulative risk over the reproductive life course, accounting for fertility and mortality levels.

Funder

European Union Horizon 2020 research and innovation programme Marie Curie Fellowship

Publisher

Oxford University Press (OUP)

Subject

General Medicine,Epidemiology

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