Testing times: Let’s leave the animals out of it-Reference-Cited by-同舟云学术

Testing times: Let’s leave the animals out of it

Published:2023-08-01 Issue:4 Volume:20 Page:13-17
ISSN:1740-9705
Container-title:Significance
language:en
Short-container-title:

Author:

Ritskes-Hoitinga Merel¹^ORCID,Watkins Justine²^ORCID,Jornick Pleun³^ORCID

Affiliation:

1. Merel Ritskes-Hoitinga is professor in evidence-based transition to animal-free innovations at the Faculty of Veterinary Medicine, Utrecht University, The Netherlands

2. Justine Watkins is a PhD candidate in risk assessment sciences at Utrecht University. She has a special focus on the use of non-animal methods in toxicology, having completed her MSc in biology at Radboud University

3. Pleun Jornick is a master’s student studying cancer, stem cells and developmental biology at Utrecht University, The Netherlands, and has a bachelor’s degree in biomedical sciences

Abstract

Abstract Monumental changes in US drug regulation have brought the justification for animal based tests into the spotlight again. Pleun Jornick, Justine Watkins and Merel Ritskes-Hoitinga explore developments in legislation, science, and technology and look forward to a world without animal testing

Publisher

Oxford University Press (OUP)

Subject

Statistics and Probability

Link

https://academic.oup.com/jrssig/article-pdf/20/4/13/51015003/qmad060.pdf

Reference8 articles.

1. Limitations of animal studies for predicting toxicity in clinical trials: Is it time to rethink our current approach?;Van Norman,2019

2. An analysis of the use of animal models in predicting human toxicology and drug safety;Bailey,2014

3. Animal to human translation: A systematic scoping review of reported concordance rates;Leenaars,2019

4. Limitations of animal studies for predicting toxicity in clinical trials: Part 2: Potential alternatives to the use of animals in preclinical trials;Van Norman,2020

5. Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment;Turner,2023