Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis, and beyond-Reference-Cited by-同舟云学术

Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis, and beyond

Published:2024-03-01 Issue:9 Volume:15 Page:642-660
ISSN:1674-800X
Container-title:Protein & Cell
language:en
Short-container-title:

Author:

Mao Chao¹^ORCID,Wang Min²,Zhuang Li¹,Gan Boyi¹³^ORCID

Affiliation:

1. Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center , Houston, TX 77030 , USA

2. Department of Molecular and Cellular Biology, Baylor College of Medicine , Houston, TX 77030 , USA

3. The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences , Houston, TX 77030 , USA

Abstract

Abstract Cell death resistance represents a hallmark of cancer. Recent studies have identified metabolic cell death as unique forms of regulated cell death resulting from an imbalance in the cellular metabolism. This review discusses the mechanisms of metabolic cell death—ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis—and explores their potential in cancer therapy. Our review underscores the complexity of the metabolic cell death pathways and offers insights into innovative therapeutic avenues for cancer treatment.

Funder

University of Texas MD Anderson Cancer Center

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/proteincell/advance-article-pdf/doi/10.1093/procel/pwae003/57086428/pwae003.pdf

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