1. Laboratory for Applied Science and Technology in Health, Carlos Chagas Institute, FIOCRUZ, Paraná, 81350-010, Brazil
2. Laboratoire de Biométrie et Biologie Évolutive, UMR 5558, CNRS, Université de Lyon, Université Lyon 1, Villeurbanne 69622, France
3. Graduate Program on Bioinformatics, Federal University of Paraná, Paraná, 81520-260, Brazil