Overlap and Mutual Distinctions Between Clinical Recovery and Personal Recovery in People With Schizophrenia in a One-Year Study-Reference-Cited by-同舟云学术

Overlap and Mutual Distinctions Between Clinical Recovery and Personal Recovery in People With Schizophrenia in a One-Year Study

Published:2021-10-29 Issue: Volume: Page:
ISSN:0586-7614
Container-title:Schizophrenia Bulletin
language:en
Short-container-title:

Author:

Dubreucq Julien¹²^ORCID,Gabayet Franck¹²,Godin Ophélia¹³,Andre Myrtille¹⁴⁵,Aouizerate Bruno¹⁶⁷,Capdevielle Delphine¹⁴⁵,Chereau Isabelle¹⁸,Clauss-Kobayashi Julie¹⁹,Coulon Nathalie¹²,D’Amato Thierry¹⁰¹¹,Dorey Jean-Michel¹²¹³,Dubertret Caroline¹¹⁴¹⁵,Faraldo Mégane¹²,Laouamri Hakim¹,Leigner Sylvain¹²,Lancon Christophe¹¹⁴¹⁵,Leboyer Marion¹³¹⁶,Llorca Pierre-Michel¹⁸,Mallet Jasmina¹¹⁴¹⁵,Misdrahi David¹¹⁷,Passerieux Christine¹¹⁸¹⁹,Rey Romain¹⁰¹¹,Pignon Baptiste¹³¹⁶^ORCID,Schorr Benoit¹⁹,Urbach Mathieu¹¹⁸¹⁹,Schürhoff Franck¹³¹⁶,Szoke Andrei¹³¹⁶,Berna F,Haffen E,Leboyer M,Llorca P M,Schürhoff F,Barteau V,Bensalem S,Godin O,Laouamri H,Souryis K,Leboyer M,Pignon B,Schürhoff F,Petrucci J,Wahiche G,Bourguignon E,Szöke A,Aouizerate B,Deloge A,Misdrahi D,Vilà E,Blanc O,Chéreau I,Denizot H,Honciuc R M,Lacelle D,Llorca P M,Pires S,Dubertret C,Mallet J,Portalier C,Coulon N,Faraldo M,Gabayet F,Leignier S,Roman C,Chesnoy-Servanin G,D’Amato T,Dorey J M,Rey R,Vehier A,Lançon C,Faget C,Metairie E,Peri P,Vaillant F,Boyer L,Fond G,Berna F,Vidailhet P,Zinetti-Bertschy A,Capdevielle D,André M,Michel T,Garbisson A,Belmonte C,Dubois T,Esselin S,Jarroir M,Passerieux C,Urbach M,Fond Guillaume¹²⁰^ORCID,Berna Fabrice¹⁹,

Affiliation:

1. Fondation FondaMental, Créteil, France

2. Centre Référent de Réhabilitation psychosociale et de Remédiation cognitive (C3R), CH Alpes Isère, Saint Egrève, France

3. Univ Paris Est Créteil, INSERM U955, IMRB, Translational Neuro-Psychiatry, Créteil, France

4. IGF, University of Montpellier, CNRS, INSERM, Montpellier, France

5. Service Universitaire de Psychiatrie Adulte, Hôpital la Colombière, CHU Montpellier, France

6. Centre Hospitalier Charles Perrens, Université de Bordeaux, Bordeaux, France

7. INRA, NutriNeuro, University of Bordeaux, Bordeaux, France

8. Université Clermont Auvergne, CMP-B CHU, CNRS, Clermont Auvergne INP, Institut Pascal, Clermont-Ferrand, France

9. Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, INSERM U1114, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France

10. INSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Center, PSYR2 team, Lyon, France

11. Centre Hospitalier le Vinatier, Centre Expert Dépression Résistante, Lyon, France

12. INSERM U1028, CNRS, UMR 5292, Lyon Neuroscience Research Center, EDUWELL Team, Lyon 2 University, Lyon, France

13. Centre Hospitalier le Vinatier, Pôle PsyPA, Lyon, France

14. AP-HP, Groupe Hospitalo-Universitaire AP-HP Nord, Service de Psychiatrie et Addictologie. Hôpital Louis Mourier, Colombes, France

15. Université de Paris INSERM UMR1266, Institute of Psychiatry and Neuroscience of Paris, Paris, France

16. AP-HP, Hôpitaux Universitaires Henri Mondor, Département Médico-Universitaire de Psychiatrie et d’Addictologie (DMU IMPACT), Fédération Hospitalo-Universitaire de Médecine de Précision en Psychiatrie (FHU ADAPT), Paris, France

17. Pôle de psychiatrie Générale et Universitaire, Centre Hospitalier Charles Perrens, Université de Bordeaux, CNRS UMR 5287-INCIA, Bordeaux, France

18. Service Universitaire de Psychiatrie d’Adultes et d’Addictologie, Centre Hospitalier de Versailles, Le Chesnay, France

19. DisAP-DevPsy-CESP, INSERM UMR1018, Université Paris-Saclay, Université Versailles Saint-Quentin-En-Yvelines, Villejuif, France

20. AP-HM, Aix-Marseille Univ, School of medicine—La Timone Medical Campus, EA 3279: CEReSS—Health Service Research and Quality of Life Center, Marseille, France

Abstract

Abstract Recovery is a multidimensional construct that can be defined either from a clinical perspective or from a consumer-focused one, as a self-broadening process aimed at living a meaningful life beyond mental illness. We aimed to longitudinally examine the overlap and mutual distinctions between clinical and personal recovery. Of 1239 people with schizophrenia consecutively recruited from the FondaMental Advanced Centers of Expertise for SZ network, the 507 present at one-year did not differ from those lost to follow-up. Clinical recovery was defined as the combination of clinical remission and functional remission. Personal recovery was defined as being in the rebuilding or in the growth stage of the Stages of Recovery Instrument (STORI). Full recovery was defined as the combination of clinical recovery and personal recovery. First, we examined the factors at baseline associated with each aspect of recovery. Then, we conducted multivariable models on the correlates of stable clinical recovery, stable personal recovery, and stable full recovery after one year. At baseline, clinical recovery and personal recovery were characterized by distinct patterns of outcome (i.e. better objective outcomes but no difference in subjective outcomes for clinical recovery, the opposite pattern for personal recovery, and better overall outcomes for full recovery). We found that clinical recovery and personal recovery predicted each other over time (baseline personal recovery for stable clinical recovery at one year; P = .026, OR = 4.94 [1.30–23.0]; baseline clinical recovery for stable personal recovery at one year; P = .016, OR = 3.64 [1.31–11.2]). In short, given the interaction but also the degree of difference between clinical recovery and personal recovery, psychosocial treatment should target, beyond clinical recovery, subjective aspects such as personal recovery and depression to reach full recovery.

Funder

Assistance Publique des Hôpitaux de Paris

Fondation FondaMental

Institut National de la Santé et de la Recherche Médicale

Publisher

Oxford University Press (OUP)

Subject

Psychiatry and Mental health

Link

http://academic.oup.com/schizophreniabulletin/advance-article-pdf/doi/10.1093/schbul/sbab114/41015727/sbab114.pdf

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