Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms

Author:

Smeland Olav B12ORCID,Wang Yunpeng134,Frei Oleksandr1,Li Wen1,Hibar Derrek P5,Franke Barbara678,Bettella Francesco1,Witoelar Aree1,Djurovic Srdjan910,Chen Chi-Hua34,Thompson Paul M5,Dale Anders M23411,Andreassen Ole A1

Affiliation:

1. NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

2. Department of Neurosciences, University of California San Diego, La Jolla, CA

3. Department of Radiology, University of California San Diego, La Jolla, CA

4. Center for Multimodal Imaging and Genetics, University of California San Diego, La Jolla, CA

5. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine of the University of Southern California, Marina del Rey, CA

6. Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands

7. Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands

8. Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands

9. Department of Medical Genetics, Oslo University Hospital, Oslo, Norway

10. NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway

11. Department of Psychiatry, University of California San Diego, La Jolla, CA

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Psychiatry and Mental health

Reference61 articles.

1. Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium;van Erp;Mol Psychiatry,2016

2. Abnormal asymmetries in subcortical brain volume in schizophrenia;Okada;Mol Psychiatry

3. Brain volumes in schizophrenia: a meta-analysis in over 18 000 subjects;Haijma;Schizophr Bull,2013

4. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study;Lichtenstein;Lancet,2009

5. Common genetic variants influence human subcortical brain structures;Hibar;Nature

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