The Pfam protein families database in 2019

Author:

El-Gebali Sara1ORCID,Mistry Jaina1,Bateman Alex1ORCID,Eddy Sean R2ORCID,Luciani Aurélien1,Potter Simon C1ORCID,Qureshi Matloob1ORCID,Richardson Lorna J1ORCID,Salazar Gustavo A1,Smart Alfredo1,Sonnhammer Erik L L3,Hirsh Layla45,Paladin Lisanna4,Piovesan Damiano4,Tosatto Silvio C E4ORCID,Finn Robert D1ORCID

Affiliation:

1. European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK

2. HHMI, Harvard University, 16 Divinity Ave Cambridge, MA 02138 USA

3. Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, 17121 Solna, Sweden

4. Department of Biomedical Sciences, University of Padua, 35131 Padova, Italy

5. Dept. of Engineering, Pontificia Universidad Católica del Perú 1801, San Miguel 15088, Lima, Perú

Funder

Horizon 2020

Wellcome Trust

Biotechnology and Biosciences Research Council

European Cooperation in Science and Technology

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference22 articles.

1. Pfam: a comprehensive database of protein domain families based on seed alignments;Sonnhammer;Proteins,1997

2. The Pfam protein families database: towards a more sustainable future;Finn;Nucleic Acids Res.,2016

3. Pfam: multiple sequence alignments and HMM-profiles of protein domains;Sonnhammer;Nucleic Acids Res.,1998

4. Accelerated profile HMM searches;Eddy;PLoS Comput. Biol.,2011

5. UniProt: the universal protein knowledgebase;The UniProt Consortium;Nucleic Acids Res.,2018

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