1. Luxembourg Centre for Systems Biomedicine, University of Luxembourg , Campus Belval, Esch-sur-Alzette L-4367, Luxembourg
2. Institut Curie, PSL Research University, INSERM U900, F-75005 Paris, France and CBIO-Centre for Computational Biology, MINES ParisTech, PSL Research University, F-75006 Paris, France
3. Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Faculty of Science, University of Leiden, Leiden 2333, The Netherlands