Gene Regulatory Enhancers with Evolutionarily Conserved Activity Are More Pleiotropic than Those with Species-Specific Activity
Author:
Publisher
Oxford University Press (OUP)
Subject
Genetics,Ecology, Evolution, Behavior and Systematics
Link
http://academic.oup.com/gbe/article-pdf/9/10/2615/22893835/evx194.pdf
Reference36 articles.
1. One billion years of bZIP transcription factor evolution: conservation and change in dimerization and DNA-binding site specificity;Mol Biol Evol,2007
2. An atlas of active enhancers across human cell types and tissues;Nature,2014
3. An integrated encyclopedia of DNA elements in the human genome;Nature,2012
4. Principles of regulatory information conservation between mouse and human;Nature,2014
5. Complex patterns of association between pleiotropy and transcription factor evolution;Genome Biol Evol,2016
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