Yeast can accommodate phosphotyrosine: v-Src toxicity in yeast arises from a single disrupted pathway

Author:

Kritzer Joshua A1,Freyzon Yelena23,Lindquist Susan23

Affiliation:

1. Department of Chemistry, Tufts University, Medford MA 02155, USA

2. Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge MA 02142, USA

3. Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge MA 02139, USA

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Applied Microbiology and Biotechnology,General Medicine,Microbiology

Reference44 articles.

1. Oncogenic kinase signalling;Blume-Jensen;Nature,2001

2. The lethality of P60(V-Src) in Saccharomyces cerevisiae and the activation of P34(Cdc28) kinase are dependent on the integrity of the Sh2 domain;Boschelli;J Cell Sci,1993

3. FLEXGene repository: from sequenced genomes to gene repositories for high-throughput functional biology and proteomics;Brizuela;Mol Biochem Parasitol,2001

4. Expression of Rous sarcoma virus transforming protein pp60v-src in Saccharomyces cerevisiae cells.;Brugge;Mol Cell Biol,1987

5. Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae;Chen;BBA-Mol Cell Res,2007

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