Pharmacological intestinal obstruction because of calcium polystyrene sulfonate administration

Author:

Thorpe Benjamin1,Vinagre Salustiano Gonzalez1,Santos Daniel2,Gomez Javier Caneiro2,Bustamante Montalvo Manuel1

Affiliation:

1. General Surgery Department , Hospital Clinico Universitario de Santiago de Compostela, Santiago de Compostela , Spain

2. Anatomical Pathology Department , Hospital Clinico Universitario de Santiago de Compostela, Santiago de Compostela , Spain

Abstract

Abstract Cation exchange resins are commonly used as treatment for hyperkalaemia in patients with chronic renal disease. There is a relation between cation exchange resins and the development of gastrointestinal adverse effects. A case of an intestinal obstruction at the terminal ileum is presented that underwent an ileocolic resection because of a critical stenosis of the intestine. The pathologist revealed abundant inflammatory cells together with deposits of calcium polystyrene crystals responsible of the intestinal obstruction. A rare cause of intestinal obstruction to bear in mind in chronically medicated patients with cation exchange resins.

Publisher

Oxford University Press (OUP)

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