Familial adenomatous polyposis: a case study-Reference-Cited by-同舟云学术

Familial adenomatous polyposis: a case study

Published:2020-10-01 Issue:10 Volume:2020 Page:
ISSN:2042-8812
Container-title:Journal of Surgical Case Reports
language:en
Short-container-title:

Author:

Yorke Joseph¹²,Yamoah Francis Akwaw¹,Awoonor-Williams Ronald¹,Konney Thomas Okpoti³,Acheampong Emmanuel⁴^ORCID,Adjei Ernest⁵,Ababio Kwabena Acheamfour⁶,Aning Daniel Gyawu¹,Afful-Yorke Dennis¹,Aidoo Freda Manu⁷,Assim Claudia Gyamfua⁸,Gyamfi Frank Enoch²^ORCID,Assim Raphael Owusu Sekyere⁷,Konadu Saabea Owusu¹,Kuwornu David Elikplim¹,Acheampong Emmanuella Nsenbah⁴

Affiliation:

1. General Surgery Unit, Directorate of Surgery, Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana

2. Department of Surgery, School of Medicine and Dentistry, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

3. Directorate of Obstetrics and Gynaecology, Kumasi, Ghana

4. Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

5. Directorate of Pathology, Komfo Anokye Teaching Hospital, Kumasi, Ghana

6. Directorate of Anaesthesia and Intensive Care, Komfo Anokye Teaching Hospital, Kumasi, Ghana

7. Directorate of Accident and Emergency, Komfo Anokye Teaching Hospital, KATH, Kumasi, Ghana

8. Directorate of Accident and Emergency, Cape Coast Teaching Hospital, Cape Coast, Ghana

Abstract

Abstract Familial adenomatous polyposis (FAP) is an inherited syndrome characterized by several adenomatous polyps of the gastrointestinal (GI) mucosa. If treatment is not provided, an average individual with classic FAP will develop colorectal carcinoma around the age of 40 years. The incidence rate of FAP in developing countries like Ghana is unknown compared to advanced countries. We present the first FAP case of a 22-year-old Ghanaian female who presented with massive lower GI bleeding and underwent surgical management after a thorough investigation. The initial assumption that colonic polyps are scarce in native Africans may be more than what is perceived. This highlights the need for the availability of endoscopic services in Ghana.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/jscr/article-pdf/2020/10/rjaa367/34036354/rjaa367.pdf

Reference10 articles.

1. Familial adenomatous polyposis syndrome: an update and review of extraintestinal manifestations;Dinarvand;Arch Pathol Lab Med,2019

2. Somatic APC mosaicism: an underestimated cause of polyposis coli;Hes;Gut,2008

3. Familial adenomatous polyposis: a case report and review of the literature;Beech;J Natl Med Assoc,2001

4. Colorectal carcinoma in west Africans: some considerations on its relatively lower incidence compared to caucasians;Irabor;Pak J Med Sci,2008

5. Lower gastrointestinal bleeding: spectrum of colonoscopy findings in ado-Ekiti, Nigeria;Ajayi;Int J Med Medic Sci,2014