Metastasis of colorectal cancer to the uterine body and fallopian tube: case report and literature review

Author:

Efetov Sergey K1ORCID,Cao Yu1ORCID,Zou Jinqi1ORCID,Dorogov Anton Y1ORCID,Paramonova Nina B2ORCID,Tsoy Larisa V2ORCID,Droshneva Inna V34,Fatyanova Anastasia S5ORCID

Affiliation:

1. Department of Faculty Surgery No.2, I.M. Sechenov First Moscow State Medical University (Sechenov University) , Moscow, 119435 , Russia

2. Insitute for Clinical Morphology and Digital Pathology, I.M. Sechenov First Moscow State Medical University (Sechenov University) , Moscow, 119435 , Russia

3. P.A. Herzen Moscow Oncology Research Institute , Branch, Nation Medical Radiology Research Center, , Moscow, 119435 , Russia

4. Ministry of Health of Russia , Branch, Nation Medical Radiology Research Center, , Moscow, 119435 , Russia

5. Department of Oncology, Radiotherapy and Reconstructive Surgery, I.M. Sechenov First Moscow State Medical University (Sechenov University) , Moscow, 119435 , Russia

Abstract

Abstract Colorectal cancer typically metastasizes to the peritoneum, liver, and lungs. However, metastases to the fallopian tube and uterus are uncommon. This case report delves into this rare occurrence of metastasis and discusses its characteristics, diagnostic methods, and treatments based on an extensive literature review. We present the case of a 61-year-old female patient who underwent her initial hospitalization for da Vinci robotic surgery to address colorectal cancer, stage pT3N0M0. However, during routine postoperative follow-up 6 months later, a localized rectal recurrence was detected. The patient commenced chemoradiotherapy with full response. Subsequently, the patient was readmitted due to pelvic pain again, and a magnetic resonance imaging scan revealed an abnormal mass in the patient’s left fallopian tube and uterine corpus, infiltrating the myometrium. Consequently, total hysterectomy with bilateral adnexectomy was performed, along with omentectomy, which confirmed metastatic involvement from rectal cancer upon postoperative pathological examination. This case may inform further diagnosis and treatment of colorectal cancer metastasis to the fallopian tube.

Publisher

Oxford University Press (OUP)

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