Gastrointestinal tuberculosis presenting as acute abdomen: a case report

Author:

Ridolfo Sofia1,Cammarata Francesco2ORCID,Bonomi Alessandro M2,Troci Albert2,Crespi Michele2,Molteni Paola1,Pellegrinelli Alessandro3,Ardizzone Sandro14,Danelli Piergiorgio24

Affiliation:

1. Department of Gastroenterology, Luigi Sacco University Hospital , Milan, Italy

2. Department of General Surgery, Luigi Sacco University Hospital , Milan, Italy

3. Department of Pathology, Luigi Sacco University of Milan , Milan, Italy

4. Department of Clinical and Preclinical Sciences, Luigi Sacco University of Milan , Milan, Italy

Abstract

Abstract Intestinal tuberculosis (ITB) represents an important diagnostic challenge in the clinical setting, as it generally can occur as a chronic condition often mimicking other diseases such as Crohn’s disease (CD), and can present itself with acute onset, which can be life-threatening. A 29-years-old Chinese woman coming to ER with abdominal pain, fever and weight loss. Computed tomography and colonoscopy images were not diagnostic. Despite medical therapy, the patient progressively worsened developing sepsis requiring emergency surgery. Pathological and microbiological examination of the colon both pointed towards gastrointestinal tuberculosis involvement. Although ITB is generally a chronic-wasting condition, it can also occur as acute abdomen representing an absolute surgical emergency. Although caseation and necrosis in granulomas can be used for diagnosis of ITB, preoperative diagnosis is still challenging. Endoscopic biopsies targeted to ulcerous lesions could be an essential diagnostic tool, contrary to those targeted to the ulcers’ edges as performed in CD.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference8 articles.

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2. Tuberculosis of the gastrointestinal tract and peritoneum;Marshall;Am J Gastroenterol,1993

3. Intestinal tuberculosis;Donoghue;Curr Opin Infect Dis,2009

4. Abdominal tuberculosis of the gastrointestinal tract: revisited;Debi;World J Gastroenterol,2014

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