Intradural extramedullary meningeal melanocytoma: a case report and literature review

Author:

Parwez Rabeeia1,Ahmed Razna2ORCID,Baig Arsalan1,Ruiz Fernanda3ORCID,Baig Mirza Asfand1ORCID,Sadek Ahmed-Ramadan1,Arvin Babak1,Qureshi Anjum1

Affiliation:

1. Department of Neurosurgery, Queens Hospital Romford , London , UK

2. GKT School of Medical Education, King’s College London , London , UK

3. Department of Neuropathology, UCL Institute of Neurology , London , UK

Abstract

Abstract Primary meningeal melanocytomas are extremely rare, benign tumours arising from the leptomeninges. While they are considered to be benign lesions, there is potential for their growth and transformation into malignant melanomas. They are commonly found in the cervical spine, with a decreased incidence in the thoracic and lumbar regions. We present a case report of a 56-year-old man who presented to our unit with a 4-month history of lower limb weakness and a sensory level at T6. Magnetic resonance imaging shows an intradural extramedullary tumour. The patient underwent a thoracic debulking of the lesion with neurophysiological monitoring. Histopathology confirmed the diagnosis of melanocytoma of meningeal origin, with a low mitotic count. Our patient recovered well post-operatively with no complications. Surgical resection is an effective method to manage this tumour; however, adjuvant radiotherapy is advised due to the risk of recurrence and malignant transformation.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference23 articles.

1. C6-T1 intradural extramedullary ventral meningeal melanocytoma resected via anterior corpectomy with reconstruction;Akgun;World Neurosurg,2020

2. Meningeal melanocytoma (“melanotic meningioma”). Its melanocytic origin as revealed by electron microscopy;Catherine Limas,1972

3. Surgical treatment for intramedullary spinal cord melanocytomas: report of 3 cases;Horn;J Neurosurg Spine,2008

4. DNA methylation-based classification of central nervous system tumours;Capper;Nature,2018

5. Cervical spinal meningeal melanocytoma presenting as intracranial superficial siderosis;Srirama Jayamma;Case Rep Radiol,2015

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