A fundamental change emerging in locally advanced rectal cancer management: a case report

Author:

Edwards-Murphy Amy12ORCID,Earley Helen1,Creavin Ben1,McCullough Peter1,Cooke Fiachra1,Neary Peter12

Affiliation:

1. Department of Academic Surgery, University Hospital Waterford , Dunmore Road, Waterford , Ireland

2. Department of Academic Surgery, University College Cork , Cork , Ireland

Abstract

Abstract Treatment of locally advanced rectal cancer remains a challenge in colorectal surgery. It has had an evolving landscape over the past three decades. Implementation of total neoadjuvant therapy (TNT) as a novel approach to management has begun globally but long-term outcomes and data analysis to identify optimal schedules are eagerly awaited. We report a case of locally advanced rectal cancer management in a young male with a complete pathological response to TNT.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference8 articles.

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3. Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial

4. Early-onset colorectal cancer: initial clues and current views;Hofseth;Nat Rev Gastroenterol Hepatol,2020

5. Non-Operative Management of Patients with Rectal Cancer: Lessons Learnt from the OPRA Trial

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