A case of high-grade mucinous tubular and spindle cell carcinoma-Reference-Cited by-同舟云学术

A case of high-grade mucinous tubular and spindle cell carcinoma

Published:2020-02-01 Issue:2 Volume:2020 Page:
ISSN:2042-8812
Container-title:Journal of Surgical Case Reports
language:en
Short-container-title:

Author:

Miura Koujin¹,Adachi Yasushi²,Shirahase Toshiaki³,Nagashima Yoji⁴,Suemune Kazuki¹,Sakaida Noriko⁵⁶,Nakano Yorika⁷,Sakai Yasuhiro⁸,Shimizu Shigeki⁹,Ikehara Susumu¹⁰

Affiliation:

1. Resident, Toyooka Hospital, Toyooka, Hyogo, Japan

2. Department of Diagnostic Pathology, Toyooka Hospital, Toyooka, Hyogo, Japan

3. Department of Urology, Toyooka Hospital, Toyooka, Hyogo, Japan

4. Department of Surgical Pathology, Tokyo Women's Medical University Tokyo, Tokyo, Japan

5. Department of Pathology and Cytology Center, BML Group PCL Japan, Ibaraki, Osaka, Japan

6. Department of Pathology, Osaka City University Graduate School of Medicine, Osaka, Osaka, Japan

7. Department of Histopathology and Cytology, Japanese Red Cross Kyoto Daini Hospital, Kyoto City, Kyoto, Kyoto, Japan

8. Department of Diagnostic Pathology, Hyogo Cancer Center, Akashi, Hyogo, Japan

9. Department of Pathology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan

10. Department of Stem Cell Disorders, Kansai Medical University, Hirakata, Osaka, Japan

Abstract

Abstract Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal cell carcinoma that initially presents as low-grade renal cell carcinoma. However, cases of MTSCC with high-grade histology and poor prognosis have been reported. Here, we report a case of MTSCC with high-grade histological features and metastasis. A 77-year-old woman consulted a hospital following frequent and painful micturition. Computed tomography scan revealed a tumor of the left kidney. First, chemotherapy was performed, with no effects. Therefore, nephrectomy was subsequently performed. Histologically, the tumor showed the features of MTSCC with sarcomatoid component. Metastasis of the tumor into the lymph node was also observed. Although adjuvant chemotherapy was performed after nephrectomy, metastasis to the lungs and bone and local recurrence was observed. The patient is still alive 2 years after nephrectomy with metastasis and recurrence of the tumor. High-grade MTSCC shows a relatively poor prognosis, specifically MTSCC with metastasis upon nephrectomy.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/jscr/article-pdf/2020/2/rjaa014/32532403/rjaa014.pdf

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