Oligometastatic colorectal adenocarcinoma to the spleen and ovaries

Author:

Heath Lucienne1ORCID,Novis Elan12,Rabindran Joel12,van Laar Veth Alexander3,Yang Tao3,Barnet Megan B245,Gett Rohan126

Affiliation:

1. Department of General Surgery, St Vincent’s Hospital , 390 Victoria St, Darlinghurst, NSW 2010 , Australia

2. Department of General Surgery, St Vincent’s Clinical School, University of New South Wales , 390 Victoria St, Darlinghurst, NSW 2010 , Australia

3. Department of Anatomical Pathology, St Vincent’s Hospital , 390 Victoria St, Darlinghurst, NSW 2010 , Australia

4. Department of Medical Oncology, Garvan Institute of Medical Research , 384 Victoria St, Darlinghurst, NSW 2010 , Australia

5. School of Biomedical Engineering, University of Technology Sydney , 11/81 Broadway Ultimo, NSW 2007 , Australia

6. Department of General Surgery, St Vincent’s Private Hospital , 406 Victoria St, Darlinghurst, NSW 2010 , Australia

Abstract

Abstract In the context of colorectal cancer, splenic and ovarian metastases are rare outside of widely disseminated disease. Growing evidence suggests that ‘oligometastatic’ or limited metastatic disease can be treated surgically with good oncological outcomes. Splenic and ovarian metastases are not well represented in studies of oligometastatic colorectal cancer, resulting in uncertainty in the best management for these patients. We present the case of a 78-year-old woman diagnosed with oligometastatic colorectal cancer to bilateral ovaries and spleen, 5 years after resection of a primary colon cancer. The patient was treated with a bilateral salpingo-oopherectomy and subsequent open splenectomy. We discuss the role of surgery and peri-operative chemotherapy in the management of oligometastatic colorectal cancer involving atypical sites.

Publisher

Oxford University Press (OUP)

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