Alliance of Genome Resources Portal: unified model organism research platform

Author:

,Agapite Julie,Albou Laurent-Philippe,Aleksander Suzi,Argasinska Joanna,Arnaboldi Valerio,Attrill Helen,Bello Susan M,Blake Judith A,Blodgett Olin,Bradford Yvonne M,Bult Carol J,Cain Scott,Calvi Brian R,Carbon Seth,Chan Juancarlos,Chen Wen J,Cherry J Michael,Cho Jaehyoung,Christie Karen R,Crosby Madeline A,Pons Jeff De,Dolan Mary E,Santos Gilberto dos,Dunn Barbara,Dunn Nathan,Eagle Anne,Ebert Dustin,Engel Stacia R,Fashena David,Frazer Ken,Gao Sibyl,Gondwe Felix,Goodman Josh,Gramates L Sian,Grove Christian A,Harris Todd,Harrison Marie-Claire,Howe Douglas G,Howe Kevin L,Jha Sagar,Kadin James A,Kaufman Thomas C,Kalita Patrick,Karra Kalpana,Kishore Ranjana,Laulederkind Stan,Lee Raymond,MacPherson Kevin A,Marygold Steven J,Matthews Beverley,Millburn Gillian,Miyasato Stuart,Moxon Sierra,Mueller Hans-Michael,Mungall Christopher,Muruganujan Anushya,Mushayahama Tremayne,Nash Robert S,Ng Patrick,Paulini Michael,Perrimon Norbert,Pich Christian,Raciti Daniela,Richardson Joel E,Russell Matthew,Gelbart Susan Russo,Ruzicka Leyla,Schaper Kevin,Shimoyama Mary,Simison Matt,Smith Cynthia,Shaw David R,Shrivatsav Ajay,Skrzypek Marek,Smith Jennifer R,Sternberg Paul W,Tabone Christopher J,Thomas Paul D,Thota Jyothi,Toro Sabrina,Tomczuk Monika,Tutaj Marek,Tutaj Monika,Urbano Jose-Maria,Auken Kimberly Van,Slyke Ceri E Van,Wang Shur-Jen,Weng Shuai,Westerfield Monte,Williams Gary,Wong Edith D,Wright Adam,Yook Karen

Abstract

Abstract The Alliance of Genome Resources (Alliance) is a consortium of the major model organism databases and the Gene Ontology that is guided by the vision of facilitating exploration of related genes in human and well-studied model organisms by providing a highly integrated and comprehensive platform that enables researchers to leverage the extensive body of genetic and genomic studies in these organisms. Initiated in 2016, the Alliance is building a central portal (www.alliancegenome.org) for access to data for the primary model organisms along with gene ontology data and human data. All data types represented in the Alliance portal (e.g. genomic data and phenotype descriptions) have common data models and workflows for curation. All data are open and freely available via a variety of mechanisms. Long-term plans for the Alliance project include a focus on coverage of additional model organisms including those without dedicated curation communities, and the inclusion of new data types with a particular focus on providing data and tools for the non-model-organism researcher that support enhanced discovery about human health and disease. Here we review current progress and present immediate plans for this new bioinformatics resource.

Funder

National Institutes of Health

National Human Genome Research Institute

National Heart, Lung, and Blood Institute

Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Genetics

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