Ensembl Genomes 2020—enabling non-vertebrate genomic research

Author:

Howe Kevin L1ORCID,Contreras-Moreira Bruno1,De Silva Nishadi1,Maslen Gareth1,Akanni Wasiu1,Allen James1,Alvarez-Jarreta Jorge1,Barba Matthieu1,Bolser Dan M1ORCID,Cambell Lahcen1,Carbajo Manuel1,Chakiachvili Marc1,Christensen Mikkel1,Cummins Carla1,Cuzick Alayne2,Davis Paul1,Fexova Silvie1,Gall Astrid1,George Nancy1,Gil Laurent1,Gupta Parul3,Hammond-Kosack Kim E2ORCID,Haskell Erin1,Hunt Sarah E1ORCID,Jaiswal Pankaj3ORCID,Janacek Sophie H1,Kersey Paul J1,Langridge Nick1,Maheswari Uma1,Maurel Thomas1,McDowall Mark D1,Moore Ben1,Muffato Matthieu1,Naamati Guy1,Naithani Sushma3ORCID,Olson Andrew4,Papatheodorou Irene1,Patricio Mateus1,Paulini Michael1,Pedro Helder1ORCID,Perry Emily1ORCID,Preece Justin3,Rosello Marc1,Russell Matthew1ORCID,Sitnik Vasily1,Staines Daniel M1,Stein Joshua4,Tello-Ruiz Marcela K4,Trevanion Stephen J1,Urban Martin2,Wei Sharon4,Ware Doreen45,Williams Gary1,Yates Andrew D1ORCID,Flicek Paul1ORCID

Affiliation:

1. European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK

2. Department of Biointeractions and Crop Protection, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK

3. Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA

4. Cold Spring Harbor Laboratory, 1 Bungtown Rd, Cold Spring Harbor, NY 11724, USA

5. USDA ARS NAA Robert W. Holley Center for Agriculture and Health, Agricultural Research Service, Ithaca, NY 14853, USA

Abstract

Abstract Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of interfaces to genomic data across the tree of life, including reference genome sequence, gene models, transcriptional data, genetic variation and comparative analysis. Data may be accessed via our website, online tools platform and programmatic interfaces, with updates made four times per year (in synchrony with Ensembl). Here, we provide an overview of Ensembl Genomes, with a focus on recent developments. These include the continued growth, more robust and reproducible sets of orthologues and paralogues, and enriched views of gene expression and gene function in plants. Finally, we report on our continued deeper integration with the Ensembl project, which forms a key part of our future strategy for dealing with the increasing quantity of available genome-scale data across the tree of life.

Funder

UK Biosciences and Biotechnology Research Council

Wellcome Trust

Medical Research Council

National Science Foundation

United States Department of Agriculture

Bill and Melinda Gates Foundation

National Human Genome Research Institute

National Institutes of Health

National Institute of Allergy and Infectious Diseases

European Union's Horizon 2020 Research and Innovation Programme

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference28 articles.

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