Protective effect of UV-irradiated red perilla (Perilla frutescens (L.) Britton) on carbon tetrachloride-induced liver injury in mice

Author:

Kurniati Dian12,Umeda Ryohei1,Kagawa Natsuko134,Goto Eiji54,Wakabayashi Ryo1,Shimada Kanae5,Hirai Shizuka1,Egashira Yukari1

Affiliation:

1. Division of Applied Biochemistry, Graduate School of Horticulture, Chiba University, 648, Matsudo, Matsudo-shi, Chiba, Japan

2. Department of Food Technology, Faculty of Agricultural Industrial Technology, Universitas Padjadjaran, Sumedang KM. 21, Jatinangor, 40600, West Java, Indonesia

3. Center for Environment, Health and Field Sciences, Chiba University, 6-2-1, Kashiwanoha Kashiwa-shi, Chiba, Japan

4. Plant Molecular Science Center, Chiba University,1-8-1 Inohana, Chuo-ku, Chiba, Japan

5. Division of Environmental Science for Bioproduction, Graduate School of Horticulture, Chiba University, 648, Matsudo, Matsudo-shi, Chiba, Japan

Abstract

Abstract UV-irradiated red perilla demonstrated promising protective effects against carbon tetrachloride-induced liver injury in mice. UV exposure significantly enhanced the accumulation of rosmarinic acid, malonylshisonin and shisonin in red perilla, and increased DPPH radical scavenging capacity. The hepatoprotective effect of UV-irradiated red perilla may be attributed to the high level of its polyphenolic compounds, which exhibit antioxidant activity.

Publisher

Informa UK Limited

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

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