Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing
Author:
Affiliation:
1. Center for Neurologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, 77 Avenue Louis Pasteur, H.I.M. 754, Boston, MA 02115, USA
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/40/19/9836/25348801/gks710.pdf
Reference32 articles.
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2. Variation in alternative splicing across human tissues;Yeo;Genome Biol.,2004
3. The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: causes and consequences;Krawczak;Hum. Genet.,1992
4. Role of RNA structure in regulating pre-mRNA splicing;Warf;Trends Biochem. Sci.,2009
5. RNA structure and the mechanisms of alternative splicing;McManus;Curr. Opin. Genet. Dev.,2011
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