Effects of different sources and levels of dietary iron and selenium on the postprandial net portal appearance of these minerals in growing pigs

Abstract

Abstract The present study compares the net portal appearance of dietary iron (Fe) and selenium (Se) after meals containing different sources and levels of these minerals. Twelve pigs (55.1 ± 3.7 kg) were used in a cross-over design to assess the 11-h net portal-drained viscera (PDV) flux of serum Fe and Se after ingestion of boluses containing inorganic (I) or organic (O) dietary Fe and Se at industry average (A; 200 and 0.6 mg, respectively) or high (H; 400 and 1.2 mg, respectively) levels. Arterial serum Fe concentrations increased by an average of 158% within 6 h post-meal and gradually decreased thereafter (P < 0.001). Values were greater (P < 0.001) for I than for O until 6 h post-meal and greater (P ≤ 0.001) for A than for H from 4 to 8 h post-meal. For the whole post-prandial period (11 h), arterial serum Fe concentrations tended (P = 0.06) to be greater for I than for O and were lowest for HO (P ≤ 0.03). Net PDV flux of Fe tended to be greater for AI than for AO (P ≥ 0.07). Cumulative appearance of Fe in PDV serum (% of dietary intake) was greater for I than for O (2.43 vs. −0.76%; P = 0.02) and A tended to be greater than H (1.96 vs. −0.29 %; P = 0.09) until 3 h post-meal, but these effects further faded out (P ≥ 0.43). Arterial serum Se concentration decreased for all treatments (average of 7%) from premeal values (P < 0.001), and this was more pronounced for O than for I (P = 0.03). Irrespective of treatment, net PDV flux of Se was positive (different from 0, P ≤ 0.03) during the first 90 min post-meal, decreased to negative minimum values (different from 0, P = 0.03) at 5 h post-meal, and was not different from 0 thereafter (P ≥ 0.11). Cumulative appearance of Se in PDV serum (% of dietary intake) was greater for I than for O (20.0 vs. −3.8%; P = 0.04) only at 45 min post-meal. In conclusion, both dietary Fe and Se absorption are limited to the early post-meal period. Whereas for Fe, the level effect is in accordance with the known negative correlation between its dietary concentration and percentage of intestinal absorption, this was not the case for dietary Se. The postabsorptive availability of dietary I was greater than O for both minerals and, particularly for Fe, at low levels.