Diet-induced obesity alters the maternal metabolome and early placenta transcriptome and decreases placenta vascularity in the mouse†

Author:

Stuart Tami J1,O’Neill Kathleen2,Condon David3,Sasson Issac2,Sen Payel4,Xia Yunwei5,Simmons Rebecca A1

Affiliation:

1. Department of Pediatrics, Division of Neonatology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA

2. Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

3. Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, Pennsylvania, USA

4. Epigenetics Center, Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

5. College of Arts and Sciences, Cornell University, Ithaca, New York, USA

Funder

KEO RSDP

KEO

TS

RAS

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,General Medicine,Reproductive Medicine

Reference95 articles.

1. Prevalence of Obesity in the United States, 2009–2010;Ogden;NCHS Data Brief,2012

2. Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews;Marchi;Obes Rev,2015

3. Impact of HIGH BMI on pregnancy: maternal and foetal outcome;Deshmukh;J Obstet Gynecol India,2016

4. The effects of maternal obesity on perinatal outcomes among those born small for gestational age;Yao;J Matern Fetal Neonatal Med,2017

5. The risk of maternal obesity to the long-term health of the offspring;O’Reilly;Clin Endocrinol,2013

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