A decade of discovery: the stunning progress of premature ovarian insufficiency research in China

Author:

Wang Xiaoyan1234,Chen Zi-Jiang1256

Affiliation:

1. Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University , Jinan, Shandong , China

2. Key laboratory of Reproductive Endocrinology of Ministry of Education, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong Provincial Clinical Medicine Research Center for Reproductive Health , Jinan, Shandong , China

3. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences , Beijing , China

4. Beijing Institute for Stem Cell and Regenerative Medicine , Beijing , China

5. Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics , Shanghai , China

6. Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai , China

Abstract

Abstract Premature ovarian insufficiency (POI) is one of the key aspects of ovarian infertility. Due to early cession of ovarian function, POI imposes great challenges on the physiological and psychological health of women and becomes a common cause of female infertility. In the worldwide, there has been a special outpouring of concern for about 4 million reproductive-aged women suffering from POI in China. Driven by advances in new technologies and efforts invested by Chinses researchers, understanding about POI has constantly been progressing over the past decade. Here, we comprehensively summarize and review the landmark development and achievements from POI studies in China spanning 2011–2020, which aims to provide key insights from bench to bedside.

Funder

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,General Medicine,Reproductive Medicine

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