Depletion of thiols leads to redox deregulation, production of 4-hydroxinonenal and sperm senescence: a possible role for GSH regulation in spermatozoa†

Author:

Ortega-Ferrusola Cristina1ORCID,Martin Muñoz Patricia2,Ortiz-Rodriguez Jose Manuel2ORCID,Anel-López Luis1ORCID,Balao da Silva Carolina3ORCID,Álvarez Mercedes1,de Paz Paulino1ORCID,Tapia Jose Antonio2ORCID,Anel Luis1ORCID,Silva- Rodríguez Antonio4,Aitken Robert J4,Gil M Cruz2ORCID,Gibb Zamira5,Peña Fernando J2ORCID

Affiliation:

1. Reproduction and Obstetrics Department of Animal Medicine and Surgery, University of León, Spain

2. Laboratory of Equine Reproduction and Equine Spermatology, Veterinary Teaching Hospital, University of Extremadura, Cáceres, Spain

3. Escola Superior Agraria de Elvas, Elvas, Portugal

4. Facility of Innovation and Analysis in Animal Source Foodstuffs, University of Extremadura, Cáceres, Spain

5. Priority Research Center in Reproductive Science, School of Environmental and Life Sciences, University of Newcastle, Callaghan, New South Wales, Australia

Funder

Ministerio de Economía y Competitividad

European Regional Development Fund

Ministerio de Educación, Cultura y Deporte

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,General Medicine,Reproductive Medicine

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