1. Department of Pharmacology, Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China
2. Guangzhou Institute of Cardiovascular Disease, Guangzhou Key Laboratory of Cardiovascular Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, PR China
3. The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, PR China
4. University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA