Spermatogonial Dio3 as a potential germ line sensor for thyroid hormone-driven epigenetic inheritance-Reference-Cited by-同舟云学术

Spermatogonial Dio3 as a potential germ line sensor for thyroid hormone-driven epigenetic inheritance

Published:2021-05-07 Issue:3 Volume:105 Page:613-615
ISSN:0006-3363
Container-title:Biology of Reproduction
language:en
Short-container-title:

Author:

Hernandez Arturo¹²³

Affiliation:

1. Center for Molecular Medicine, Maine Medical Center Research Institute, Maine Health, Scarborough, ME, USA

2. Department of Medicine, Tufts University School of Medicine, Boston, MA, USA

3. Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, USA

Abstract

Thyroid hormone-clearing type 3 deiodinase is located in spermatogonia, where it may serve as a critical modulator of the thyroid hormone exposure of the male germ line and its epigenetic information, with implications for neurodevelopmental and endocrine disorders in subsequent generations.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Mental Health

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,General Medicine,Reproductive Medicine

Link

http://academic.oup.com/biolreprod/advance-article-pdf/doi/10.1093/biolre/ioab089/38336770/ioab089.pdf

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